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Chicken and Spinach Casserole with Cream Cheese

This creamy and indulgent chicken casserole features tender, seasoned chicken breasts topped with a rich cream cheese and spinach mixture, all covered in melted mozzarella. Perfect for busy weeknights and keto-friendly diets.
Prep Time 20 minutes
Cook Time 25 minutes
Total Time 45 minutes
Servings: 4 portions
Course: Dinner, Main Course
Cuisine: American
Calories: 528

Ingredients
  

  • 2 large boneless, skinless chicken breasts cut horizontally to create 4 thin cutlets
  • 2 tablespoons olive oil divided
  • 3 cloves garlic minced
  • 1 tablespoon Italian seasoning
  • 1/4 teaspoon salt
  • 1/2 teaspoon black pepper
  • 2 cups fresh spinach or 1 cup frozen, thawed and squeezed dry
  • 8 ounces cream cheese softened to room temperature
  • 1 cup shredded mozzarella cheese divided (1/2 cup in filling, 1/2 cup for topping)
  • 1/2 cup Parmesan cheese optional but recommended

Equipment

  • 9x13 inch baking dish
  • Large mixing bowl
  • Medium skillet
  • meat thermometer
  • whisk

Method
 

  1. Preheat your oven to 400°F (200°C) and lightly grease a 9x13-inch baking dish with cooking spray or butter.
  2. Cut each chicken breast horizontally to create four thin cutlets. Use a meat mallet to gently pound any thicker ends to ensure even thickness throughout.
  3. In a large bowl, whisk together 1 tablespoon of olive oil, minced garlic, Italian seasoning, salt, and black pepper. Add the chicken cutlets and toss to coat. Cover and refrigerate for 15-30 minutes to marinate.
  4. Heat the remaining 1 tablespoon of olive oil in a medium skillet over medium heat. Add the fresh spinach and cook for 2-3 minutes, stirring occasionally, until completely wilted. Remove from heat and set aside to cool slightly.
  5. In a medium bowl, beat the softened cream cheese until smooth and creamy. Stir in the cooked spinach, 1/2 cup of the mozzarella cheese, and Parmesan cheese if using. Mix until well combined.
  6. Optional step: For added flavor and color, heat a skillet over medium-high heat and sear the marinated chicken cutlets for 1-2 minutes per side until lightly browned. This step can be skipped to save time.
  7. Arrange the chicken cutlets in the prepared baking dish in a single layer. Spread the cream cheese and spinach mixture evenly over each piece of chicken. Sprinkle the remaining 1/2 cup mozzarella cheese over the top.
  8. Bake in the preheated oven for 20-30 minutes, until the chicken reaches an internal temperature of 165°F (75°C) on a meat thermometer and the cheese is melted and lightly browned on top.
  9. Remove from oven and let the casserole rest for 5 minutes before serving. This allows the juices to redistribute and the filling to set slightly for easier serving.

Notes

For frozen spinach, make sure to thaw completely and squeeze out all excess moisture to prevent a watery casserole. Full-fat cream cheese provides the richest texture and flavor. Always use a meat thermometer to ensure chicken reaches 165°F internal temperature. Searing the chicken before baking is optional but adds extra flavor and appearance. Store leftovers in an airtight container in the refrigerator for up to 3 days or freeze for up to 2 months.
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